Dr. James Matthew Knight is a board-certified dermatologist and board-certified Mohs surgeon with more than 25 years of experience in medical, surgical, and oncologic dermatology. He is the founder of Knight Dermatology Institute and currently serves as Chief of Dermatology for Orlando Health. Throughout his career, Dr. Knight has become widely recognized for his expertise in skin cancer diagnosis, Mohs micrographic surgery, dermatologic surgery, and comprehensive skin health management.
In addition to his clinical practice, Dr. Knight founded and served as the first director of the Orlando Health UF Health Melanoma & Skin Cancer Center. His work combines advanced technology, surgical precision, and evidence-based medicine to help patients achieve the best possible outcomes in skin cancer prevention, early detection, and treatment.
Dermatology plays a critical role in both skin health and disease prevention. Regular dermatologic evaluations can help identify suspicious lesions, chronic skin conditions, and potentially serious diseases at earlier stages when treatment may be most effective. Patients throughout Orlando, Winter Park, Lake Mary, and Central Florida seek specialized dermatology care for preventive screenings, skin cancer management, and comprehensive skin health services.
• Orlando Health — Orlando, FL — (321) 841-5111
• Orlando Health UF Health Melanoma & Skin Cancer Center — Orlando, FL
Accepted Insurance Providers: Florida Blue, Cigna Healthcare, Oscar Health
Patients should verify appointment availability, accepted insurance plans and current professional information directly with the healthcare provider before scheduling a consultation.